A sample part printed with a 0.25mm nozzle came out rather lumpy, so I wanted to use my smallest nozzle, 0.15mm. I've used it before, but it's so small it can be finicky. My previous project was printed in Nylon, which takes a lot of heat... and can be hard to clean out of the hotend. Sure enough, it caused the worst clogs I've ever seen. I could sometimes get some cleaning filament through, but it would repeatedly gum up again. The 0.25 nozzle was clogged and I had to use a heat gun and some very small cleaning wires to get it clear. Then the "heat break" portion of the hotend was also clogged. I had to use a drill bit and some careful hammer taps to get it cleared.
I finally figured out that the hotend was not getting as hot as it used to, barely reaching the temperature needed to melt the Nylon. So there was not enough heat to permeate the whole hotend and nozzle, which explains why I could not get it cleaned out well. Fortunately I also have some 0.15mm cleaning wires, which are really hard to insert. I finally got it working well enough to get residual PLA out of the 0.15 nozzle and do some test prints.